Hmm, most hotels in the metro area (especially the con ones) will at least have a hotel safe. If you're paying $100+ a night, then in-room are usually standard (working with dealers means you learn where the safes are... ;). Give them a call and find out if you decide to go the cash route.

Otherwise, I tend to give housekeeping a break, and myself piece of mind, and have them NOT clean my room all week. No way it's gonna get that dirty in four days anyway. ;)